Accepted 10th July, 2015


Host-pathogen interaction is a different and complex type of association. Some Host-pathogen interaction does not cause clinically evident disease, while some of them lead to mortality.  This interaction is mediated through special type of biomolecules called adhesion molecule.  These adhesion molecule shows high affinity towards their specific receptor which present on the host cell surface.  Adhesion molecule considered as potent virulence factor, that facilitate the infection, during the time of host cell invasion which mean Host-pathogen interaction.  The accentuation of this session is to encompass the concept of Host-pathogen interaction that causes disease.  Moreover to understand how adhesion molecules damage   host immunity and   pathogen survives in host body.


Key word: M. tuberculosis, Adhesion molecules, Fibronectin, Fibronectin binding proteins.